Micro-sized, needle-shaped booster — Tingling Ampoule

Drawing upon the principles of microneedling, Medicube crafted a micro-sized, needle-shaped booster to target a range of skin issues. Enhanced with patented Exosome shots, this formula physically delivers active ingredients to pores, providing daily intensive treatment for home use. Clinically validated to care for pore size, smooth skin texture, strengthen the skin barrier, and promote a radiant complexion.

A tingling sensation is natural — it may last for some time, but rest assured this is a normal reaction to the Zero Exosome Shot.

• INTENSE (25000) — the highest strength level, with 25,000 exosome-coated spicules
• Non-comedogenic, tested to be low-irritating, gluten-free, no artificial color
• Net wt. 1.01 fl.oz. / 30ml

Skin Type: Combination, Dry, Normal, Oily, Sensitive
Skin Concerns: Acne / Blemishes, Blackhead / Whitehead, Oiliness, Pores, Uneven Texture

Key Ingredients

Exosome-coated Spicule (Hydrolyzed Sponge) — needle-like micro-particles that create pathways for active ingredients, then naturally shed with dead skin over several days.

Lacto Exosome — sourced from Lactobacillus, delivering proteins and skin-supporting materials deep into the skin.

AHA + BHA + PHA — a gentle exfoliating trio (Citric Acid, Betaine Salicylate, Gluconolactone) that refines texture and clears pores.

Niacinamide & Panthenol — brighten tone and soothe while supporting the skin barrier.

Study Results

• Absorption of active ingredients in cosmetics +242% compared to standalone use
• Pore care: pore density −21.1%, pore area −15.3%, pore volume −16.7%
• Dead skin cells improvement +88.7%, radiance +51.7%, skin barrier enhancement +54.2%

Excerpt from Medicube Exosome Shot Test Report and Survey. Results may vary.

How To Use

Standard: After cleansing, apply to your entire face (avoiding eyes and lips) as the first step in your skincare routine. Gently rub and press with your hands so the needle-like formula absorbs deep into your skin. Finish with a water-based moisturizer. Do not rinse off — it acts as a pathway that boosts absorption of your following skincare.

Usage notes: Avoid the eye and lip areas. For sensitive skin, do a patch test first. Tingling, redness, itching, or a heat sensation may occur — this is a natural reaction. Adjust amount and frequency based on your skin's sensitivity.

Full Ingredients (INTENSE 25000)

Water, Glycereth-26, Dipropylene Glycol, Butylene Glycol, Caprylic/Capric Triglyceride, Niacinamide, Calcium Aluminum Borosilicate, Hydrolyzed Sponge, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, 1,2-Hexanediol, Caprylyl Glycol, Isohexadecane, Glycerin, Polysorbate 80, Carbomer, Tromethamine, Panthenol, Ethylhexylglycerin, Adenosine, Sorbitan Oleate, Sorbitan Isostearate, Polysorbate 60, Disodium EDTA, Lactobacillus Extracellular Vesicles (154 ppm), Kummerowia Striata Extract, Oenothera Biennis (Evening Primrose) Flower Extract, Ulmus Davidiana Root Extract, Pinus Palustris Leaf Extract, Pueraria Lobata Root Extract, Cinchona Pubescens Bark Extract, Gluconolactone, Betaine Salicylate, Citric Acid, Milk Exosomes (10 ppm), Leptospermum Scoparium Leaf Extract, Hydrogenated Lecithin, Polyglyceryl-10 Laurate, Ceramide NP, Acetyl Tetrapeptide-5, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-5